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Why is Rezulin a problem?

Rezulin can cause serious liver damage (toxicity) that, in some cases, results in death. Symptoms of liver toxicity include: abdominal pain, nausea, vomiting, dark urine, jaundice, fatigue, and loss of appetite. Rezulin has also been linked to a thickening of the left ventricular wall of the heart, a condition that can ultimately lead to heart failure and death. There have been an estimated 430 Rezulin patients that suffered liver failure, including 391 deaths. It was found that a Rezulin patient’s risk of liver failure is increased 1,200 times by taking the diabetes drug.

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